Chimeric antigen receptors (CARs) incorporating mutations in the IgG4 Fc spacer region to eliminate Fc receptor recognition results in improved CAR T cell persistence and anti-tumor efficacy

Jonnalagadda, M., Mardiros, A., Hoffman, L., Bernanke, A., Chang, W.-C., Bretzlaff, W., … Forman, S. J. (2013). Chimeric antigen receptors (CARs) incorporating mutations in the IgG4 Fc spacer region to eliminate Fc receptor recognition results in improved CAR T cell persistence and anti-tumor efficacy. Journal for ImmunoTherapy of Cancer, 1(S1). https://doi.org/10.1186/2051-1426-1-s1-p18