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Journal Article

A monoclonal antibody recognizing an iscosapeptide sequence in the heavy chain of human factor XII inhibits surface-catalyzed activation.

Advances in experimental medicine and biology (1989) 247 A 473-476
DOI: 10.1007/978-1-4615-9543-4_72
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Abstract

A monoclonal antibody (mAb B7C9) to human factor XII was produced which blocked the surface mediated coagulant activity of factor XII but not the amidolysis of H-D-ProPheArg-pNA. The mAb epitope was localized to a 20 amino acid sequence of 2.5 kDa in the heavy chain of factor XII.

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Pixley, R. A., & Colman, R. W. (1989). A monoclonal antibody recognizing an iscosapeptide sequence in the heavy chain of human factor XII inhibits surface-catalyzed activation. Advances in Experimental Medicine and Biology, 247 A, 473–476. https://doi.org/10.1007/978-1-4615-9543-4_72

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