Delayed diagnosis of primary bone and soft tissue tumors initially treated as degenerative spinal disorders

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Abstract

Background Symptoms of primary bone and soft tissue tumors located in the trunk mimic those of degenerative spinal disorders such as low back pain or pain or numbness of the legs. Due to their rarity, especially in sarcoma located in the trunk, diagnosis is sometimes delayed. Methods A retrospective review was performed of the records of 383 patients with primary bone and soft tissue tumors who visit our out patient clinic from 2011 to 2013 at a single institution. Patients with delayed diagnosis of primary bone and soft tissue tumors initially treated as degenerative spinal disorders for more than 2 months were identified. Results Of the 383 patients, 5 (1.3%) were initially diagnosed as having degenerative spinal disorders. All 5 patients had bone or soft tissue tumors in the lumbar spine or pelvis. Three patients had a malignant tumor (osteosarcoma, chondrosarcoma, or small round cell sarcoma) at the progressive stage, and 1 died of lung metastasis. Two patients had a benign tumor (aneurysmal bone cyst or simple bone cyst). Conclusions Our findings suggest that when low back pain and leg pain are refractory to conservative treatment, further radiological examination should be conducted.

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Nishisho, T., Sakai, T., Tezuka, F., Higashino, K., Takao, S., Takata, Y., … Sairyo, K. (2016). Delayed diagnosis of primary bone and soft tissue tumors initially treated as degenerative spinal disorders. Journal of Medical Investigation, 63(3–4), 274–277. https://doi.org/10.2152/jmi.63.274

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