p-Boronophenylalanine (p-BPA) has been used for Boron Neutron Capture Therapy (BNCT). The synthetic route to p-BPA was developed by Snyder et al. 1. o- and m-Boronophenylalanine (o- and m-BPA) are the isomers of p-BPA, and they may be incorporated into melanoma cells such as p-BPA and used for BNCT. Even if this incorporation dose not happen, this will give us informations about the relationship between structure and incorporation. Therefore, we have developed a way of synthesizing o-BPA and m-BPA.
CITATION STYLE
Yoshino, K., Maruyama, T., Takahashi, H., Mori, Y., Kakihana, H., Mishima, Y., … Shiono, M. (1993). Synthesis of o- and m-Boronophenylalanine. In Advances in Neutron Capture Therapy (pp. 261–264). Springer US. https://doi.org/10.1007/978-1-4615-2978-1_53
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