Abstract
A symposium report. An improved synthetic methodol. for the solid-phase synthesis of long-chain b-peptides is described. The method was tested by synthesizing dodecapeptide and tetracosapeptide by coupling single amino acids and a series of homologous peptides by coupling b-peptidic triades. b-Tripeptide precursor Fmoc-(b-HAla-b-HLys(Boc)-b-HPhe)-OH was synthesized in eight steps from the corresponding a-amino acids with an overall yield of 60%. [on SciFinder (R)]
Cite
CITATION STYLE
Frackenpohl, J., Schreiber, J. V., Arvidsson, P. I., & Seebach, D. (2001). Recent Advances in the Solid-Phase Synthesis of Long-Chain β-Peptides. In Peptides: The Wave of the Future (pp. 275–276). Springer Netherlands. https://doi.org/10.1007/978-94-010-0464-0_125
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