Effect of salinomycin on fermentation and nitrogen metabolism in the artificial rumen

Abstract

Peptidase activities against Ala 3 , Ala 4 and Phe 3 were increased (P < 0.05) by salinomycin, whereas activities against Ala 5 and Phe 4 were unchanged and that against Gly-Arg-MNA was decreased (P < 0.05). In the presence of salinomycin, the main products of peptide hydrolysis were single amino acids, whereas dipeptides were formed in samples from control vessels. Key words: Ionophores, salinomycin, peptidases, peptide, Rusitec