Concise methods for the synthesis of chiral polyoxazolines and their application in asymmetric hydrosilylation

Abstract

Seven polyoxazoline ligands were synthesized in high yield in a one-pot reaction by heating polycarboxylic acids or their esters and chiral β-amino alcohols under reflux with concomitant removal of water or the alcohol produced in the reaction. The method is much simpler and more efficient in comparison to those methods reported in the literature. © 2010 Li et al.