Researches on application of stem cell therapy in exercise-induced spinal cord injury recovery

Abstract

Exercise-induced spinal cord injury can easily cause hypoaesthesia, hypokinesia and also irreversible damages to reflection function and bring huge burdens both to patients and the whole society. Currently, it is difficult to find one effective therapy for exercise-induced spinal cord injury. Stem cell technology progress has created good opportunities for exercise-induced spinal cord injury recovery. Through searching the research literatures related to stem cell technology and its application in exercise-induced spinal cord injury prevention and treatment, this thesis is aimed to analyze and explore stem cell therapy application in exercise-induced spinal cord injury and to discuss stem cell transplantation applications in spinal cord injury recovery, stem cell neurotrophic factor's role in spinal cord injury recovery and researches on stem cell therapy of gene modification as well as spinal cord injury recovery, so as to provide scientific proof and theory basis for the repair and treatment of exercise-induced spinal cord injury. Stem cell's such properties as transplantation, migration, self-renewal and multi-differentiation make it inevitable for stem cell to be applied into exercise-induced spinal cord injury recovery. © 2011 Springer-Verlag Berlin Heidelberg.