Abstract
Summary: We introduce here a novel acquisition and processing methodology for cross-polarization based 1D rotating-frame relaxation dispersion NMR experiments. This easy-to-use protocol greatly facilitates the screening, acquisition, processing and model fitting of large on- and off-resonance R1ρ relaxation dispersion NMR datasets in an automated manner for the analysis of chemical exchange phenomena in biomolecules.
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Walinda, E., Morimoto, D., Nishizawa, M., Shirakawa, M., & Sugase, K. (2016). Efficient identification and analysis of chemical exchange in biomolecules by R1ρ relaxation dispersion with Amaterasu. Bioinformatics, 32(16), 2539–2541. https://doi.org/10.1093/bioinformatics/btw188
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