Abstract
The main causes for knee arthroplasty revision later than 5 years in the study by Sharkey et al. [42] were polyethylene wear and aseptic loosening. Polyethylene wear has become a concern in total knee arthroplasty (TKA), because it has been stated as the main cause for osteolysis [1]. The presence of polyethylene particles in the joint, which are phagocytised by macrophages and giant cells [2], causes the release of many proinflammatory interleukins, which activate the osteoclasts, the main responsible cells for osteolysis [4, 22, 24].
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CITATION STYLE
Gomez, P. H., & Jurado, I. P. (2013). In vivo wear of highly crosslinked polyethylene in total knee arthroplasty. In Tribology in Total Hip and Knee Arthroplasty: Potential Drawbacks and Benefits of Commonly Used Materials (Vol. 9783642452666, pp. 51–61). Springer-Verlag Berlin Heidelberg. https://doi.org/10.1007/978-3-642-45266-6_6
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