Skip to main content
Journal ArticleOPEN ACCESS

Dendritic cells matured in the presence of TLR ligands overcome the immunosuppressive functions of regulatory T cells

  • Berk E
  • Xu S
  • Czerniecki B
OncoImmunology (2014) 3(2) e27617
DOI: 10.4161/onci.27617
N/ACitations
Citations of this article
5Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Toll like receptor (TLR)-stimulated dendritic cells (DCs) are able to overcome the inhibitory activity of regulatory T cells (Tregs) and induce the proliferation of effector T cells. TLR-activated DCs secrete a soluble factor and act directly on Tregs to convert them into interferon γ-secreting TH1-like cells that express the transcription factor T-bet.

Cite

CITATION STYLE

APA

Berk, E., Xu, S., & Czerniecki, B. J. (2014). Dendritic cells matured in the presence of TLR ligands overcome the immunosuppressive functions of regulatory T cells. OncoImmunology, 3(2), e27617. https://doi.org/10.4161/onci.27617

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free