oposSOM-Browser: an interactive tool to explore omics data landscapes in health science

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Abstract

Background: oposSOM is a comprehensive, machine learning based open-source data analysis software combining functionalities such as diversity analyses, biomarker selection, function mining, and visualization. Results: These functionalities are now available as interactive web-browser application for a broader user audience interested in extracting detailed information from high-throughput omics data sets pre-processed by oposSOM. It enables interactive browsing of single-gene and gene set profiles, of molecular ‘portrait landscapes’, of associated phenotype diversity, and signalling pathway activation patterns. Conclusion: The oposSOM-Browser makes available interactive data browsing for five transcriptome data sets of cancer (melanomas, B-cell lymphomas, gliomas) and of peripheral blood (sepsis and healthy individuals) at www.izbi.uni-leipzig.de/opossom-browser.

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Loeffler-Wirth, H., Reikowski, J., Hakobyan, S., Wagner, J., & Binder, H. (2020). oposSOM-Browser: an interactive tool to explore omics data landscapes in health science. BMC Bioinformatics, 21(1). https://doi.org/10.1186/s12859-020-03806-w

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