Rates of hospitalization associated with the use of aldosterone receptor antagonists in patients with pulmonary arterial hypertension

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Abstract

We show that spironolactone use was associated with an increased rate of all-cause hospitalizations, but no difference in hospitalizations for heart failure or pulmonary arterial hypertension, in patients with World Health Organization Group 1 pulmonary arterial hypertension. A possible reason for this finding is confounding from retrospective study design.

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Corkish, M. E., Devine, L. T., Clarke, M. M., Murray, B. P., & Rose-Jones, L. J. (2019). Rates of hospitalization associated with the use of aldosterone receptor antagonists in patients with pulmonary arterial hypertension. Pulmonary Circulation, 9(3). https://doi.org/10.1177/2045894019868422

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