Smoking history and long-term outcomes post PCI by sex, from FU-Registry

Abstract

Objective: Most important lifestyle factor for the primary and secondary prevention for coronary heart diseases is smoking. However, few reported on the relationship between smoking habits/history and long-term outcomes post PCI procedures. Methods: From our PCI- Registry (FU-Registry), 829 PCI cases (497 males, 332 females) whose 5 years follow-up data including clinical outcomes were available, were used. Results: In males, no difference was observed in patient’s background or lesion characteristics between smoker and never smoker groups, however, smoking (+) showed high incidence of dyslipidemia, statin use at first PCI, but as for clinical outcomes are similar between the groups. For females, smoking (+) group showed low HDL-C (48.3 +12.8mg/dL vs. 51.5+13.4mg/dL, p< 0.01), and lesion reference was significantly smaller than smoking (-) group. No difference was observed in medications, while smoking (+) showed high complication of ASO. Conclusions: Females were less smokers than males, while female smokers showed low HDL-C levels at PCI and then longterm outcomes (including MACEs) were more frequent in smokers than never smokers.