Cytokines and Related Metabolic Markers in Adult Neuropsychiatric Disorders: Possible Roles in Clinical Application

Abstract

The importance of inflammatory response system activation indicated by abnormalities in cytokines and related metabolic markers in adult psychiatric disorders has been well studied and documented. The important aspects were reported not only in terms of pathophysiological mechanisms but also from the aspect of early diagnosis, prediction of the course of disease and prediction of response to treatment and subgrouping of clinical diagnostic groups. Future application of those markers in early diagnosis, prediction and prevention of suicide and personalized medicine for choice of treatment, either with psychotropic medications or adjuvant therapy, is necessary. The innovation effort to bring those results to application is challenging. New therapeutic developments should be carried out with great care. The past and present findings from the aspect of clinical applications and future perspectives are discussed in this chapter.