Encapsulation of Alendronate in Chitosan based Polymeric Nanoparticles for Effective Management of Osteoporosis – Development to Release Kinetic Study

Abstract

Osteoporosis means 'Porous bone' is a disease characterized by progressive bone thinning. The deterioration of bone tissue can lead to bone fragility and fracture, especially of the hip, spine, shoulder and wrist. Osteoporosis is characterized by decreasing bone mineral density (BMD). Bisphosphonates are the most commonly prescribed drugs for the treatment of osteoporosis in the US and many other countries including India.