A-glucosidase and α-amylase inhibition of some ethanolic propolis samples

Abstract

Propolis is a natural product, and it is of a great interest due to the possible uses of non-synthetic supplements in improving metabolic disorders. To support this claim, the current study was designed and presented. In this study, six propolis extracts obtained from different location of Turkey were investigated to prove the beneficial therapeutic properties such as inhibition potent against some enzymes and levels of antioxidant. IC50results of α-glucosidase (0.208-0.426 mg/mL) and α-amylase (0.487-0.938 mg/mL) were found the variable range. Moreover, antioxidant results of them were given to support the inhibition degrees. According to the total phenolic (TPC) and antioxidant data, S4 was noted as the most efficient sample. Future studies are needed to investigate the biological effects of propolis, but the ultimate evaluating showed that it could be a significant source thanks to its nutritional and clinical potential.