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Book Chapter

Fungal Drug Resistance: Azoles

  • Lopez-Ribot J
  • Wiederhold N
  • Patterson T
Springer International Publishing, (2017), 397-405
DOI: 10.1007/978-3-319-46718-4_27
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Abstract

Azole antifungal agents are widely used in the clinical arena to treat a variety of fungal infections. The azoles inhibit fungal lanosterol demethylase, a key fungal enzyme in the ergosterol biosynthetic pathway, leading to an altered membrane physiology and, most...

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Lopez-Ribot, J. L., Wiederhold, N. P., & Patterson, T. F. (2017). Fungal Drug Resistance: Azoles. In Antimicrobial Drug Resistance (pp. 397–405). Springer International Publishing. https://doi.org/10.1007/978-3-319-46718-4_27

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