Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates

Abstract

See, stats, and : http : / / www. researchgate. net / publication / 259970276 Multiple Urine ARTICLE DOI : 10 . 11648 / j . ajbio . 20140201 . 12 READS 76 8 , INCLUDING : Abdul Hazara 15 SEE Iqbal Hazara 5 SEE All - text , letting . Available : Abdul Retrieved : 10 Abstract : Transmission of bacterial strains between patients is a serious problem in hospitals and with the increasing rate of antibiotic resistance the problem has farther escalated . Enterobacteriaceae produced ESBLs , especially E - coli , are increasingly important nosocomial pathogens . These bacteria are often multiple resistant and are responsible for many intestinal infections and urinary tract infections . Urine samples [ 4010 ] were collected cultured and the bacterial isolates were identified in this study , 1000 isolates showed significant bacterial growth . Among the sample 1000 showed bacterial growth in which E . coli strains was most common 58 . 5% of the 1000 bacterial isolates from urine cultures , gram negative rods accounted for 95 . 30 % , while gram positive cocci accounted for the test 4 . 70 % . Total pathogen isolated and recovered is distributed as K . pneumoniae 16 . 7 % , Enterobacter spp 0 . 57 % , P . aeruginosa 14 . 5 % , Proteus spp 1 . 34 % Enterococci 1 . 05 % , S . aurus 0 . 76 % and E . faecalis 2 . 87 % , A . calcoaceticus 1 . 05 % , Enterobacter spp 0 . 57 % E . agglumarance 2 . 20 % serratia 0 . 1 % . In case of g negative bacteria 58 [ 2 . 45 % ] were ESBL producers and 379 [ 47 . 54 % ] were MDR . while in case of gram positive 2 [ 0 . 2 % ] were MRSA . Resistance has arisen to all antibiotics introduced into general clinical practice and is likely to arise to any new antibiotics introduced in the future . It is therefore imperative to consider what can be done to minimize the development and transfer of antibiotics resistance gene clusters . Methods can be developed to minimize antibiotic resistance .