A Copper-Catalyzed Tandem Cyclization Reaction of Aminoalkynes with Alkynes for the Construction of Tetrahydropyrrolo[1,2-a]quinolines Scaffold

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Abstract

A synthetic method for diversely substituted tetrahydropyrrolo[1,2-a]quinolines was developed via CuCl-catalyzed cascade transformation of internal aminoalkynes with alkynes under microwave- irradiation.

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Ma, C. L., Zhao, J. H., Yang, Y., Zhang, M. K., Shen, C., Sheng, R., … Hu, Y. Z. (2017). A Copper-Catalyzed Tandem Cyclization Reaction of Aminoalkynes with Alkynes for the Construction of Tetrahydropyrrolo[1,2-a]quinolines Scaffold. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-16887-0

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