The synthesis of 2-substituted-trifluoromethylquinolines from aniline, trifluoromethylanilines, 3-aminoquinoline and trifluoromethylquinaldines is reported. In vitro antileishmanial evaluation of 2-alkyl, 2-alkenyl and 2-epoxypropyl-trifluoromethylquinolines is presented.
CITATION STYLE
Dade, O., Provot, J., Moskowitz, H., Mayrargue, J., & Prina, E. (2001). Synthesis of 2-substituted trifluoromethylquinolines for the evaluation of leishmanicidal activity. Chemical and Pharmaceutical Bulletin, 49(4), 480–483. https://doi.org/10.1248/cpb.49.480
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