Engineered niches model the onset of metastasis

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Abstract

A humanized biomaterial microenvironment that mimics the pre-metastatic niche captures disseminated tumour cells and recapitulates metastatic progression after implantation in xenografted mice.

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Matei, I., Rampersaud, S., & Lyden, D. (2018). Engineered niches model the onset of metastasis. Nature Biomedical Engineering, 2(12), 885–887. https://doi.org/10.1038/s41551-018-0326-7

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