Skip to content

Focus on the agents most frequently responsible for perioperative anaphylaxis

3Citations
Citations of this article
28Readers
Mendeley users who have this article in their library.

This artice is free to access.

Abstract

Adverse reactions (ARs) to drugs administered during general anesthesia may be very severe and life-threatening, with a mortality rate ranging from 3 to 9%. The adverse reactions to drugs may be IgE and non-IgE-mediated. Neuromuscular blocking agents (NMBA) represent the first cause of perioperative reactions during general anesthesia followed by latex, antibiotics, hypnotic agents, opioids, colloids, dyes and antiseptics (chlorhexidine). All these substances (i.e. NMBA, anesthetics, antibiotics, latex devices) may cause severe systemic non-IgE-mediated reactions or fatal anaphylactic events even in the absence of any evident risk factor in the patient's anamnesis. For this reason, in order to minimize perioperative anaphylactic reactions, it is important to have rapid, specific, sensitive in vitro diagnostic tests able to confirm the clinical diagnosis of acute anaphylaxis.

Cite

CITATION STYLE

APA

Di Leo, E., Delle Donne, P., Calogiuri, G. F., Macchia, L., & Nettis, E. (2018, July 9). Focus on the agents most frequently responsible for perioperative anaphylaxis. Clinical and Molecular Allergy. BioMed Central Ltd. https://doi.org/10.1186/s12948-018-0094-7

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free