Synthesis, identification, biological activity and anti-cancer activity Studies of Hetrocyclic Ligand Azo-schiff Base with Au(III) Complex

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Abstract

This research involved preparation of 2-((E)-(1H-benzo.[d]imidazol-2-yl).diazenyl)-4-(((4-bromophenyl)imino)methyl)phenol and Au(III) complex which was prepared by mixing solution of metal salt with ligand solution at mole ratio[ M:L] 1:1 . Compounds prepared were identified by FT- IR,, elemental analyses (C.H.N). Molar conductance measurements, magnetic susceptibility UV-Visb. The biological activity of the compounds prepared were examined against the susceptible organisms Streptococcus, (Gram. Positive) and Escherichia coli ,(Gram .negative), as antibacterial and Penicillium. Sp and Aspergillus Niger as antifungal, The prepared compounds checked for anti-cancer activity; activity of anti-tumor against of breast cancer for human.

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Hessoon, H. M., & Karam, F. F. (2022). Synthesis, identification, biological activity and anti-cancer activity Studies of Hetrocyclic Ligand Azo-schiff Base with Au(III) Complex. Egyptian Journal of Chemistry, 65(1), 327–334. https://doi.org/10.21608/EJCHEM.2021.80392.3980

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