In vitro hydroxyapatite-forming ability and antimicrobial properties of mesoporous bioactive glasses doped with Ti/Ag

Abstract

Mesoporous bioactive glasses (MBGs) doped with Ti/Ag were synthesized. The structural, morphological, and textural properties of all samples were investigated by small-angle X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy, and N2 adsorption-desorption technique. In vitro hydroxyapatite- (HAP-) induced growth and antimicrobial properties of these materials were investigated in detail. These results indicate that MBGs-Ti/Ag possess faster HAP-induced growth and higher sterilization rate than the pure MBGs materials. With Ti/Ag doping, these functional MBGs show the improved characteristics and have more promising potential in bone-tissue regeneration systems and surgery. © 2013 Huiming Lin et al.