Cellulose acetate electrophoresis of mouse hemoglobins modified with the disulfide reagent cystamine permits rapid, unequivocal discrimination of all combinations of the codominant mouse hemoglobin "single" (Hbb s) and "diffuse" (Hbb d and Hbb p) alleles. The single, diffuse major, diffuse d-minor, and diffuse p-minor adult hemoglobins are all resolved by this method, which depends on the presence of a cysteine in the β chains of "diffuse" mice which is not found in the β chain of "single" mice. © 1978 Plenum Publishing Corporation.
CITATION STYLE
Whitney, J. B. (1978). Simplified typing of mouse hemoglobin (Hbb) phenotypes using cystamine. Biochemical Genetics, 16(7–8), 667–672. https://doi.org/10.1007/BF00484723
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