Biomedical applications of Durio zibethinus extract mediated gold nanoparticles as antimicrobial, antioxidant and anticoagulant activity

Abstract

An eco-friendly and efficient method has been used for green synthesis of stable gold nanoparticles (Au NPs) using Durio zibethinus extract as a reducing and capping agent. The biologically produced nanoparticles were characterized by UV-Vis, XRD, SEM, EDAX and TEM analysis. The elemental composition of Au NPs was reported by EDAX spectral analysis. The bio-reduced Au NPs exhibited almost spherical. Increasing applications of NPs especially metallic nanoparticle plays an important role. Gold is one of the most useful metallic nanoparticles. Au NPs having unique physiochemical characteristics and wide usage in different field applications. Besides, antibacterial, antioxidant and anticoagulant properties of Au NPs were studied. It is proved that Au NPs synthesized using natural reducing agents (plant leaves, route, seeds, pulp, stem, etc.) are eco-friendly, inexpensive, have good anti-microbial activities against micro-organisms. This study established a synthesis of Au NPs using Durio zibethinus extract as a viable green route approach, with remarkable antimicrobial, antioxidant and anticoagulant activities. As far as we know, this is the first report of the use of Durio zibethinus extract to synthesize Au NPs.