Community-acquired methicillin-resistant Staphylococcus aureus meningitis complicated by cerebral infarction. Role of antibiotic combination of linezolid plus levofloxacin

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Abstract

The therapeutic options available for central nervous system (CNS) infections due to resistant Grampositive cocci remain limited. We report an unusual case of community-acquired methicillin-resistant Staphylococcus aureus meningitis complicated by cerebral infarction in the middle cerebral artery territory in a previously healthy young male. After an initial vancomycin-based regimen, treatment was completed with a seven-week course of linezolid and levofloxacin. The potential role of such a combination and, particularly, linezolid as a first-line therapy in serious CNS infections is also discussed. © 2010 The Japanese Society of Internal Medicine.

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Fernández-Ruiz, M., Cervera, C., Pitart, C., Pérez, G., del Río, A., Miró, J. M., … Moreno, A. (2010). Community-acquired methicillin-resistant Staphylococcus aureus meningitis complicated by cerebral infarction. Role of antibiotic combination of linezolid plus levofloxacin. Internal Medicine, 49(18), 1971–1974. https://doi.org/10.2169/internalmedicine.49.3942

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