Transient interactions in metalloproteins

Abstract

Transient protein complexes, with short lifetimes, are the result of compromise between the specificity and the instability of the binding. For metalloproteins, such features are even more pronounced because they are often engaged in electron transfer processes. Understanding the dynamics of the redox transient metallo-interactome and, in particular, of the interactions involving biomimetic interfaces requires a challenge based on specific proteomic tools. © 2011 The Authors Journal compilation © 2011 FEBS.