A better understanding of the functions sphingolipids play in living organisms can be achieved by analyzing the biochemical and physiological changes that result from genetic alterations of sphingolipid metabolism. This review summarizes the current knowledge gained from studies both on human patients and mutant animals (mice, cats, dogs, and cattle) with genetic disorders of sphingolipid metabolism. Genetic alterations affecting the biosynthesis, transport, or degradation of simple sphingolipids are discussed. © Springer-Verlag Wien 2013.
CITATION STYLE
Albinet, V., Bats, M. L., Bedia, C., Sabourdy, F., Garcia, V., Ségui, B., … Levade, T. (2013). Genetic disorders of simple sphingolipid metabolism. Handbook of Experimental Pharmacology, 215, 127–152. https://doi.org/10.1007/978-3-7091-1368-4_7
Mendeley helps you to discover research relevant for your work.