Reversible hyperkinetic movement disorder related to quetiapine withdrawal: A case report

Abstract

Quetiapine is used in treatment of schizophrenia, schizoaffective and bipolar disorders as well as psychosis in Parkinson's disease (PD) patients. Neurological side effects are not uncommon with this drug. However, there is limited knowledge about quetiapine withdrawal extra-pyramidal side effects. More recently quetiapine is used for sleep disorders and behaviour abnormalities in PD and its related syndrome. Therefore withdrawal dyskinesias may become more widely observed in the future, and patients need to be warned against sudden discontinuation of the drug. We present a rare case of Quetiapine withdrawal and discussing his bizarre abnormal movement.