How we manage prostate biopsy and prostate cancer therapy in men with haemophilia

Abstract

A 56-year-old African American male with severe haemophilia A [baseline factor VIII (FVIII) activity <1%] and chronic hepatitis C virus infection started annual serial monitoring of prostate-specific antigen (PSA) at age 40 because of a family history of prostate cancer (his father died from the disease at age 63). His most recent PSA level was 4.4ngL -1 ; previous values were <3ngL -1. Digital rectal examination was unrevealing. © 2012 Blackwell Publishing Ltd.