We observed above that the effect of the KPQ mutation of the SCN5A gene leading to a delayed sodium current can be modeled by increasing the reaction rates from the inactivated state to the open state and to the permissible state C0. The model gave results at least qualitatively similar to the experimental data.
CITATION STYLE
Tveito, A., & Lines, G. T. (2016). The burst mode of the mutant sodium channel. In Lecture Notes in Computational Science and Engineering (Vol. 111, pp. 223–236). Springer Verlag. https://doi.org/10.1007/978-3-319-30030-6_14
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