Prediction of secondary structures conserved in multiple RNA sequences

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Abstract

RNA structure is conserved by evolution to a greater extent than sequence. Predicting the conserved structure for multiple homologous sequences can be much more accurate than predicting the structure for a single sequence. RNAstructure is a software package that includes the programs Dynalign, Multilign, TurboFold, and PARTS for predicting conserved RNA secondary structure. This chapter provides protocols for using these programs.

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Xu, Z. Z., & Mathews, D. H. (2016). Prediction of secondary structures conserved in multiple RNA sequences. In Methods in Molecular Biology (Vol. 1490, pp. 35–50). Humana Press Inc. https://doi.org/10.1007/978-1-4939-6433-8_3

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