Copy number variations are important polymorphisms that can infl uence gene expression within and close to the rearranged region, and results in phenotypic variation. Techniques that detect abnormalities in DNA copy number are therefore useful for studying the associations between DNA aberrations and disease phenotype and for locating critical genes. PCR-based detection of copy number of target gene using TaqMan copy number assay offers a reliable method to measure copy number variation in human genome.
CITATION STYLE
Mehrotra, M. (2016). PCR-based detection of DNA copy number variation. In Methods in Molecular Biology (Vol. 1392, pp. 27–32). Humana Press Inc. https://doi.org/10.1007/978-1-4939-3360-0_3
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