A vaccine for ischemic stroke

Abstract

Poor adherence to secondary prevention in poststroke patients is one of the major causes for recurrence of ischemic stroke. Vaccination is a promising strategy for overcoming this limitation because of its long-term effects; however, it may have an increased risk of long-term side effects as well. Nevertheless, our recent studies reported that a vaccine against S100A9 and Ang II was effective without causing any major side effects. In this chapter, we present the history of vaccination for ischemic stroke and the possible use of antithrombotic and antihypertensive vaccines as secondary prevention measures in poststroke patients.