Genetics of lumbar disk degeneration

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Abstract

The etiology of LBP is complex and involves multiple factors, with disk degeneration of the lumbar spine being a major contributor. This chapter aims to equip readers with a basic understanding of genetics and introduce the principles and findings of genetic studies in lumbar disk degeneration (LDD), following a general framework for genetic studies of all complex diseases.

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Cheung, K. M. C., Li, Y., Sham, P. C., & Chan, D. (2016). Genetics of lumbar disk degeneration. In Advanced Concepts in Lumbar Degenerative Disk Disease (pp. 67–88). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-662-47756-4_6

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