A comparison of liprotamase, a non-porcine pancreatic enzyme replacement therapy, to porcine extracted pancrelipase in a noninferiority randomized clinical trial in patients with cystic fibrosis

  • Konstan M
  • Wagener J
  • Wilschanski M
  • et al.
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Abstract

… Concomitant medications for treatment of cystic fibrosis, including CF transmembrane conductance regulator (CFTR) modulators, GAS, and … Liprotamase failed to achieve the primary endpoint in the SOLUTION trial. The change from baseline CFA to end of study was minimal for …

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Konstan, M. W., Wagener, J. S., Wilschanski, M., Laki, I., Boas, S. R., Sands, D., … Pennington, J. (2018). A comparison of liprotamase, a non-porcine pancreatic enzyme replacement therapy, to porcine extracted pancrelipase in a noninferiority randomized clinical trial in patients with cystic fibrosis. Clinical Investigation, 08(04). https://doi.org/10.4172/clinical-investigation.1000141

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