Phentolamine Infusion Therapy

Abstract

Phentolamine (phentolamine mesylate), a non-selective alpha-adrenergic receptor antagonist, has traditionally been used in hypertensive crises due to pheochromocytoma, extravasation management, and local anesthesia reversal. But recent research has also suggested applications beyond these indications including uses for abdominal cancer pain and neuropathic pain.