Flexible 3D Plasmonic Web Enables Remote Surface Enhanced Raman Spectroscopy

Abstract

Nanoplasmonic materials concentrate light in specific regions of dramatic electromagnetic enhancement: hot spots. Such regions can be employed to perform single molecule detection via surface-enhanced Raman spectroscopy. However, this phenomenon is challenging since hot spots are expected to be highly intense/abundant and positioning of molecules within such hot spots is crucial to manage with ultrasensitive SERS. Herein, it is discovered that a 3D plasmonic web embedded within a biohybrid (3D-POWER) exhibits plasmonic transmission, spontaneously absorbs the analyte, and meets these so much needed criteria in ultrasensitive SERS. 3D-POWER is built with nanopaper and self-assembled layers of graphene oxide and gold nanorods. According to in silico experiments, 3D-POWER captures light in a small region and performs plasmonic field transmission in a surrounding volume, thereby activating a plasmonic web throughout the simulated volume. The study also provides experimental evidence supporting the plasmonic field transport ability of 3D power, which operates as a SERS signal carrier (even beyond the apparatus field of view), and the ultrasensitive behavior of this ecofriendly and flexible material facilitating yoctomolar limit of detection. Besides, 3D-POWER is proven useful in food and biofluids analysis. It is foreseen that 3D-POWER can be employed as a valuable platform in (bio)analytical applications.