COVID-19 is now pandemic throughout the world, and scientists are searching for effective therapies to prevent or treat the disease. The combination of curcumin and piperine is a potential option for the management of COVID-19 based on several mechanisms including antiviral, anti-inflammatory, immunomodulatory, antifibrotic, and antioxidant effects. Here, we describe the probable mechanism of curcumin-piperine against COVID-19. Administration of curcumin-piperine combination appears as a potential strategy to counterbalance the pathophysiological features of COVID-19 including inflammation. The optimal dose and duration of curcumin-piperine supplementation should be determined in the future.
CITATION STYLE
Miryan, M., Soleimani, D., Askari, G., Jamialahmadi, T., Guest, P. C., Bagherniya, M., & Sahebkar, A. (2021). Curcumin and Piperine in COVID-19: A Promising Duo to the Rescue? In Advances in Experimental Medicine and Biology (Vol. 1327, pp. 197–204). Springer. https://doi.org/10.1007/978-3-030-71697-4_16
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