An asymmetric synthesis of an advanced tetracyclic intermediate toward the synthesis of bielschowskysin (1) is described. A biomimetic [2 + 2]-photocyclization was used to establish the cyclobutane core of bielschowskysin. Macrocyclization under Heck conditions led to an unprecedented carbo-oxygenation of a 1,1-disubstituted double bond. © 2013 American Chemical Society.
CITATION STYLE
Himmelbauer, M., Farcet, J. B., Gagnepain, J., & Mulzer, J. (2013). A palladium-catalyzed carbo-oxygenation: The bielschowskysin case. Organic Letters, 15(12), 3098–3101. https://doi.org/10.1021/ol401285d
Mendeley helps you to discover research relevant for your work.