Hemodynamic Consequences of Changes in Microvascular Structure

25Citations
Citations of this article
38Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

In hypertension, an increased media-to-lumen ratio of small resistance arteries might play an important role in the increase of vascular resistance, and may also be an adaptive response to the increased hemodynamic load. The presence of morphological alteration in the microvasculature may be associated to an impaired tissue perfusion and/or to the development of target organ damage. Structural alterations in the microcirculation might represent a predictor of the onset of cardio-cerebrovascular events and hypertension complications. A cross-talk between the small and large artery may exaggerate arterial damage, following a vicious circle. Therefore, in the present review, possible hemodynamic consequences of the presence of microvascular structural alterations will be considered, in terms of their time of onset, role in the development and/or maintenance of high blood pressure values, and interrelationships with structural/mechanical alterations of large conductance arteries.

Cite

CITATION STYLE

APA

Rizzoni, D., Agabiti-Rosei, C., & Agabiti-Rosei, E. (2017, October 1). Hemodynamic Consequences of Changes in Microvascular Structure. American Journal of Hypertension. Oxford University Press. https://doi.org/10.1093/ajh/hpx032

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free