Preparation and biological properties of saccharide-modified gold nanoparticles

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Abstract

The gold nanoparticels were modified by biological active saccharides, and the properties of gold nanoparticle including protein recognition abilities were investigated. First, the gold nanoparticle with a diameter of about 8 nm was modified by lactose-substituted mercapto oligoethylene. The gold nanoparticle was water soluble, and aggregated by addition of the specific recognition lectin. Then, the gold nanoparticle with a diameter of 40 nm was prepared by glycopolymer cattying α-mannoside. The gold nanoparticle with mannose was readily water soluble, and showed pink colour. The UV-adsorption of the gold nanoparticle was increased by addition of the specific recognition lectin of Concanavalin A though other protein didn't change the UV spectra.

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APA

Toyoshima, M., Ooya, K., Miura, Y., & Kobayashi, K. (2007). Preparation and biological properties of saccharide-modified gold nanoparticles. Funtai Oyobi Fummatsu Yakin/Journal of the Japan Society of Powder and Powder Metallurgy, 54(12), 843–848. https://doi.org/10.2497/jjspm.54.843

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