The relationship between hypothyroidism and polycystic ovary syndrome

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Abstract

Introduction: The association of polycystic ovary syndrome with other metabolic disorders and cardiovascular diseases has been documented; nevertheless, its relationship with autoimmune disorders is not clearly established, however, an important prevalence of thyroid disorders has been found in this group of patients. Objective: To describe the different existing theories that can explain the relationship between hypothyroidism and polycystic ovary syndrome along with its possible impact on associated morbidities. Method: A search was conducted in PubMed and LILACS with the keywords of“Polycystic ovary syndrome”,“Hypothyroidism”,“Thyroid disease”and with its respective Spanish terms, in July 2020. Results: 51 articles related to the subject were selected, published in the last 10 years. The pathogenesis between both disorders is not clearly established. An important impact has been found at the metabolic level in this group of patients and it is considered that their cardiovascular risk could be increased. Conclusions: Considering the significant prevalence and complications that both short and long term, women with both alterations could have, it is necessary to discuss the need for the exclusion of hypothyroidism from the diagnostic criteria applied for the syndrome, early screening of the syndrome, and the study of the therapeutic implications that its approach brings.

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Guzmán-López, J. A., Rivera-Contreras, O. E., & Sepúlveda-Agudelo, J. (2021, September 1). The relationship between hypothyroidism and polycystic ovary syndrome. Revista Chilena de Obstetricia y Ginecologia. Sociedad Chilena de Obstetricia y Ginecologia. https://doi.org/10.24875/RECHOG.M21000031

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