N-Methyl-isosalsoline from Hammada scoparia

Abstract

The title compound (systematic name: 1,2-dimethyl-6-meth-oxy-1,2,3,4-tetra- hydro-isoquinolin-7-ol), C12H17NO2, is a major alkaloid isolated from Hammada scoparia leaves. It belongs to the isoquinoline family and it was characterized by NMR spectroscopy and X-ray crystallographic techniques. The absolute configuration could not be reliably determined. An intermolecular O - H⋯N hydrogen bond is present in the crystal structure.