Pathophysiology of hypertensive renal damage

23Citations
Citations of this article
68Readers
Mendeley users who have this article in their library.

Abstract

Rived relaxing factor. Increased transit of proteinladen fluid into the mesangial space also may mediate hypertensive nephrosclerosis. Several studies have provided encouraging evidence that antihypertensive therapy, particularly with angiotensinconverting enzyme inhibitors or calcium antagonists, can slow the progression of renal damage. Am J Hy- pertens 1993:6:241S-244SThe kidney may contribute to and be damaged by hypertension. Evidence from studies of renal transplant recipients and familial studies suggests a genetic component for the occurrence of hypertension and nephrosclerosis. Glomerular injury may result from glomerular hypertension caused by loss of autoregulation and afferent renal vasodilatation. Glomerular injury may be mediated by injury to endothelial cells, which, having lost their thromboresistance, may initiate intravascular coagulation and alter the balance between endothelin and endothelium-de. © 1993 by the American Journal of Hypertension, Ltd.

References Powered by Scopus

Hyperfiltration in remnant nephrons: A potentially adverse response to renal ablation

1732Citations
N/AReaders
Get full text

Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat

1057Citations
N/AReaders
Get full text

EARLY AGGRESSIVE ANTIHYPERTENSIVE TREATMENT REDUCES RATE OF DECLINE IN KIDNEY FUNCTION IN DIABETIC NEPHROPATHY

850Citations
N/AReaders
Get full text

Cited by Powered by Scopus

Ischemic renal diseases: New insights into old entities

154Citations
N/AReaders
Get full text

The role of angiotensin II and plasminogen activator inhibitor-1 in progressive glomerulosclerosis

121Citations
N/AReaders
Get full text

Is microalbuminuria a marker of early intrarenal vascular dysfunction in essential hypertension?

97Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Ritz, E., Fliser, D., & Siebels, M. (1993). Pathophysiology of hypertensive renal damage. American Journal of Hypertension, 6(7), 241S-244S. https://doi.org/10.1093/ajh/6.7.241S

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 14

58%

Researcher 6

25%

Professor / Associate Prof. 3

13%

Lecturer / Post doc 1

4%

Readers' Discipline

Tooltip

Medicine and Dentistry 24

69%

Pharmacology, Toxicology and Pharmaceut... 6

17%

Biochemistry, Genetics and Molecular Bi... 3

9%

Nursing and Health Professions 2

6%

Save time finding and organizing research with Mendeley

Sign up for free