Materials advances enabled by nanotechnology have brought about promising approaches to improve the encapsulation mechanism for immunoisolated cell-based drug delivery. Cell-based drug delivery is a promising treatment for many diseases but has thus far achieved only limited clinical success. Treatment of insulin dependent diabetes mellitus (IDDM) by transplantation of pancreatic β-cells represents the most anticipated application of cell-based drug delivery technology. This review outlines the challenges involved with maintaining transplanted cell viability and discusses how inorganic nanoporous membranes may be useful in achieving clinical success. © 2010 Landes Bioscience and Springer Science+Business Media.
CITATION STYLE
Mendelsohn, A., & Desai, T. (2010). Inorganic nanoporous membranes for immunoisolated cell-based drug delivery. Advances in Experimental Medicine and Biology, 670, 104–125. https://doi.org/10.1007/978-1-4419-5786-3_10
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