Background: The eosinophilic response to clozapine is well described in the literature, causing a variety of responses, from serositis to colitis. However, there are not case reports describing a clozapine-induced marked eosinophilia resulting in multiorgan dysfunction. Case presentation: In this case report, we describe a 24 year old Caucasian male who presented with severe systemic eosinophilia resulting in eosinophilic GI tract infiltration, myocarditis, pericardial and pleural effusions with dramatic improvement following drug withdrawal. Conclusions: Clozapine associated eosinophilia should be suspected in the setting of eosinophilic infiltration of multiple organs.
CITATION STYLE
Marchel, D., Hart, A. L., Keefer, P., & Vredeveld, J. (2017). Multiorgan eosinophilic infiltration after initiation of clozapine therapy: A case report. BMC Research Notes, 10(1). https://doi.org/10.1186/s13104-017-2662-1
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