Self-assembled tiO2 nanocrystal clusters for selective enrichment of intact phosphorylated proteins

Abstract

Mesoporous traps: The title clusters were fabricated through self-assembly of nanocrystals In emulsion droplets and subsequent protective calcination. The specific affinity offered by the metal oxide and the size-exclusion mechanism enabled by the mesoporous structure enable the use of these clusters for efficient enrichment of intact phosphorylated proteins from complex biological samples (see picture). (Figure Presented) © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.